Identification of Phyllanthus niruri by FTIR Spectroscopy with Chemometrics

Phyllanthus niruri (Indonesian: meniran) is a crude drug used in scientific jamu for hyperuricemia, mild hypertension, osteoarthritis, hemorrhoids, and hypercholesterolemia. This plant contains various bioactive compounds such as flavonoids, terpenes, coumarins, lignans, tannins, saponins, alkaloids, etc. wild growing the tropics sub-tropics of Asia, America, China. herb grows well from lowlands to highlands, bushes, terrain, yards, roadsides, gardens, rivers. The levels active can vary depending on many factors, location, temperature, humidity, rainfall, others. research aimed evaluate differentiate P. herbs according their geographical location using FTIR fingerprint coupled with chemometrics, Principal Component Analysis (PCA) Cluster (CA). results this study showed that 14 samples are classified into two groups. first group consists powder originating Tawangmangu, Kediri, Surabaya, Bangkalan, Gresik, Mojokerto, Kertosono, Krian, Blitar, Nganjuk, unknown 1, 2, 3, whereas second only one sample Pasuruan. In conclusion, analyzed chemometrics adequate collected different locations. fingerprints combined be further considered method quality control process .